Temecula is a city in southwestern Riverside County, California. The city is a tourist and resort destination. Temecula's 2022 population was 111,752. Spanning more than 33,000 acres, the largest viticultural area in Southern California, Temecula Valley Wine Country is one of the state’s best-kept secrets. First planted in 1968, the region is now home to nearly 50 wineries, from boutique to large-production, rustic to modern.