Twain Harte is a charming community located in Tuolumne County, California, USA. It is nestled in the Sierra Nevada Mountains, offering a picturesque setting in the heart of Tuolumne County. It is situated at an elevation of approximately 3,900 feet (1,200 meters). The population was 2,226 at the 2010 census, down from 2,586 at the 2000 census.